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The tumor suppressor RhoBTB1 controls Golgi integrity and breast cancer cell invasion through METTL7B

BACKGROUND: RhoBTB1 and 2 are atypical members of the Rho GTPase family of signaling proteins. Unlike other Rho GTPases, RhoBTB1 and 2 undergo silencing or mutation in a wide range of epithelial cancers; however, little is known about the consequences of this loss of function. METHODS: We analyzed t...

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Publicado en:BMC Cancer
Main Authors: McKinnon, Caroline M., Mellor, Harry
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319017/
https://ncbi.nlm.nih.gov/pubmed/28219369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3138-3
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