Exploration of the role of gene mutations in myelodysplastic syndromes through a sequencing design involving a small number of target genes

Novel sequencing designs are necessary to supplement the recognized knowledge of myelodysplastic syndrome (MDS)-related genomic alterations. In this study, we sequenced 28 target genes in 320 Chinese MDS patients but obtained 77.2% of recall factors and 82.8% of genetic abnormalities (including kary...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Feng, Wu, Ling-Yun, He, Qi, Wu, Dong, Zhang, Zheng, Song, Lu-Xi, Zhao, You-Shan, Su, Ji-Ying, Zhou, Li-Yu, Guo, Juan, Chang, Chun-Kang, Li, Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318910/
https://ncbi.nlm.nih.gov/pubmed/28220884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43113
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