Pan-neurexin perturbation results in compromised synapse stability and a reduction in readily releasable synaptic vesicle pool size

Neurexins are a diverse family of cell adhesion molecules that localize to presynaptic specializations of CNS neurons. Heterologous expression of neurexins in non-neuronal cells leads to the recruitment of postsynaptic proteins in contacting dendrites of co-cultured neurons, implicating neurexins in...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Quinn, Dylan P., Kolar, Annette, Wigerius, Michael, Gomm-Kolisko, Rachel N., Atwi, Hanine, Fawcett, James P., Krueger, Stefan R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318902/
https://ncbi.nlm.nih.gov/pubmed/28220838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42920
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