Autophagy Protects Advanced Glycation End Product-Induced Apoptosis and Expression of MMP-3 and MMP-13 in Rat Chondrocytes

Aging is one of the most prominent risk factors for the pathological progression of osteoarthritis (OA). One feature of age-related changes in OA is advanced glycation end products (AGEs) accumulation in articular cartilage. Autophagy plays a cellular housekeeping role by removing dysfunctional cell...

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Publicat a:Biomed Res Int
Autors principals: Huang, Wenzhou, Ao, Peng, Li, Jian, Wu, Tianlong, Xu, Libiao, Deng, Zhongbo, Chen, Wenjie, Yin, Changchang, Cheng, Xigao
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318618/
https://ncbi.nlm.nih.gov/pubmed/28265573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6341919
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