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Assessment of the Role of NO-cGMP Pathway in Orthodontic Tooth Movement Using PDE5 Inhibitors: An Animal Study

OBJECTIVES: Nitric oxide (NO) is a signaling molecule that mediates mechanical bone loading. Cyclic guanosine 3′, 5′ monophosphate (cGMP) is a NO-induced effector molecule. The aim of this study was to assess the effect of NO-cGMP pathway on orthodontic tooth movement (OTM) in rats by use of two pho...

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Bibliographische Detailangaben
Veröffentlicht in:J Dent (Tehran)
Hauptverfasser: Mirhashemi, Amir Hossein, Akhoundi, Mohammad Sadegh Ahmad, Ghazanfari, Rezvaneh, Etemad-Moghadam, Shahroo, Alaeddini, Mojgan, Khorshidian, Azam, Dehpour, Ahmad Reza, Momeni, Nafiseh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tehran University of Medical Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318494/
https://ncbi.nlm.nih.gov/pubmed/28243299
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