Wide Distribution of Foxicin Biosynthetic Gene Clusters in Streptomyces Strains – An Unusual Secondary Metabolite with Various Properties

Streptomyces diastatochromogenes Tü6028 is known to produce the polyketide antibiotic polyketomycin. The deletion of the pokOIV oxygenase gene led to a non-polyketomycin-producing mutant. Instead, novel compounds were produced by the mutant, which have not been detected before in the wild type strai...

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Udgivet i:Front Microbiol
Main Authors: Greule, Anja, Marolt, Marija, Deubel, Denise, Peintner, Iris, Zhang, Songya, Jessen-Trefzer, Claudia, De Ford, Christian, Burschel, Sabrina, Li, Shu-Ming, Friedrich, Thorsten, Merfort, Irmgard, Lüdeke, Steffen, Bisel, Philippe, Müller, Michael, Paululat, Thomas, Bechthold, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318452/
https://ncbi.nlm.nih.gov/pubmed/28270798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00221
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