Tamoxifen differentially regulates miR-29b-1 and miR-29a expression depending on endocrine-sensitivity in breast cancer cells

Endocrine-resistance develops in ~ 40% of breast cancer patients after tamoxifen (TAM) therapy. Although microRNAs are dysregulated in breast cancer, their contribution to endocrine-resistance is not yet understood. Previous microarray analysis identified miR-29a and miR-29b-1 as repressed by TAM in...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Muluhngwi, Penn, Krishna, Abirami, Vittitow, Stephany L., Napier, Joshua T., Richardson, Kirsten M., Ellis, Mackenzie, Mott, Justin L., Klinge, Carolyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318263/
https://ncbi.nlm.nih.gov/pubmed/27986463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.12.007
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