Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy.
Retinal capillary closure induced by hyperglycemia is the principal pathophysiologic abnormality underlying diabetic retinopathy, but the mechanisms by which this induction occurs are not clear. Treatment of diabetic rats for 26 weeks with aminoguanidine, an inhibitor of advanced glycosylation produ...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1763069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11555 |
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