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Carfilzomib boosted combination therapy for relapsed multiple myeloma

Carfilzomib is a proteasome inhibitor that binds selectively and irreversibly to the 20S proteasome, the proteolytic core particle within the 26S proteasome, resulting in the accumulation of proteasome substrates and ultimately growth arrest and apoptosis of tumor cells. The development and ultimate...

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Bibliografski detalji
Izdano u:Onco Targets Ther
Glavni autori: Steiner, Raphael E, Manasanch, Elisabet E
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317297/
https://ncbi.nlm.nih.gov/pubmed/28243125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S102756
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