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Carfilzomib boosted combination therapy for relapsed multiple myeloma

Carfilzomib is a proteasome inhibitor that binds selectively and irreversibly to the 20S proteasome, the proteolytic core particle within the 26S proteasome, resulting in the accumulation of proteasome substrates and ultimately growth arrest and apoptosis of tumor cells. The development and ultimate...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Autores principales: Steiner, Raphael E, Manasanch, Elisabet E
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317297/
https://ncbi.nlm.nih.gov/pubmed/28243125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S102756
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