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Mechanistic Investigation on ROS Resistance of Phosphorothioated DNA
Phosphorothioated DNA (PT-DNA) exhibits a mild anti-oxidant property both in vivo and in vitro. It was found that 8-OHdG and ROS levels were significantly lower in dnd+ (i.e. S(+)) E. coli., compared to a dnd− (i.e. S(−)) strain. Furthermore, different from traditional antioxidants, phosphorothioate...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316992/ https://ncbi.nlm.nih.gov/pubmed/28216673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42823 |
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