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A pan-cancer analysis of secreted Frizzled-related proteins: re-examining their proposed tumour suppressive function
Secreted frizzled-related proteins (SFRPs), containing five family members (SFRPs 1–5) are putative extracellular Wnt inhibitors. Given their abilities to inhibit Wnt signalling, as well as the loss of SFRP1 in many cancers, this family is generally considered to be tumour suppressive. In this study...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316967/ https://ncbi.nlm.nih.gov/pubmed/28218291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42719 |
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