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A 3′-5′ exonuclease activity embedded in the helicase core domain of Candida albicans Pif1 helicase

3′-5′ exonucleases are frequently found to be associated to polymerases or helicases domains in the same enzyme or could function as autonomous entities. Here we uncovered that Candida albicans Pif1 (CaPif1) displays a 3′-5′ exonuclease activity besides its main helicase activity. These two latter a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wei, Xiao-Bin, Zhang, Bo, Bazeille, Nicolas, Yu, Ying, Liu, Na-Nv, René, Brigitte, Mauffret, Olivier, Xi, Xu-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316945/
https://ncbi.nlm.nih.gov/pubmed/28216645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42865
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