Infection-derived lipids elicit an immune deficiency circuit in arthropods

The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that...

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Foilsithe in:Nat Commun
Main Authors: Shaw, Dana K., Wang, Xiaowei, Brown, Lindsey J., Chávez, Adela S. Oliva, Reif, Kathryn E., Smith, Alexis A., Scott, Alison J., McClure, Erin E., Boradia, Vishant M., Hammond, Holly L., Sundberg, Eric J., Snyder, Greg A., Liu, Lei, DePonte, Kathleen, Villar, Margarita, Ueti, Massaro W., de la Fuente, José, Ernst, Robert K., Pal, Utpal, Fikrig, Erol, Pedra, Joao H. F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316886/
https://ncbi.nlm.nih.gov/pubmed/28195158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14401
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