Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions

BACKGROUND AND AIMS: One major obstacle of hepatitis B virus (HBV) research is the lack of efficient cell culture system permissive for viral infection and replication. The aim of our study was to establish a robust HBV infection model by using hepatocyte-like cells (HLCs) derived from human pluripo...

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Bibliographic Details
Published in:J Hepatol
Main Authors: Xia, Yuchen, Carpentier, Arnaud, Cheng, Xiaoming, Daniel Block, Peter, Zhao, Yao, Zhang, Zhensheng, Protzer, Ulrike, Liang, T. Jake
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316493/
https://ncbi.nlm.nih.gov/pubmed/27746336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.10.009
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