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Metabolic stress-induced phosphorylation of KAP1 Ser473 blocks mitochondrial fusion in breast cancer cells

Mitochondrial dynamics during nutrient starvation of cancer cells likely exert profound effects on their capability for metastatic progression. Here we report that KAP1 (TRIM28), a transcriptional co-adaptor protein implicated in metastatic progression in breast cancer, is a pivotal regulator of mit...

詳細記述

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書誌詳細
出版年:Cancer Res
主要な著者: Cheng, Chun-Ting, Kuo, Ching-Ying, Ouyang, Ching, Li, Chien-Feng, Chung, Yiying, Chan, David C., Kung, Hsing-Jien, Ann, David K.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316485/
https://ncbi.nlm.nih.gov/pubmed/27364555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2921
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