Salsalate treatment following traumatic brain injury reduces inflammation and promotes a neuroprotective and neurogenic transcriptional response with concomitant functional recovery

Neuroinflammation plays a critical role in the pathogenesis of traumatic brain injury (TBI). TBI induces rapid activation of astrocytes and microglia, infiltration of peripheral leukocytes, and secretion of inflammatory cytokines. In the context of modest or severe TBI, such inflammation contributes...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Brain Behav Immun
Päätekijät: Lagraoui, Mouna, Sukumar, Gauthaman, Latoche, Joseph R., Maynard, Sean K., Dalgard, Clifton L., Schaefer, Brian C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316369/
https://ncbi.nlm.nih.gov/pubmed/27939247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.12.005
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