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Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy
BACKGROUND: Diabetic cardiomyopathy is a major risk factor in diabetic patients but its pathogenesis remains poorly understood. The ubiquitin-proteasome system (UPS) facilitates protein quality control by degrading unnecessary and damaged proteins in eukaryotic cells, and dysfunction of UPS is impli...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316366/ https://ncbi.nlm.nih.gov/pubmed/27913284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.11.013 |
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