Intra-accumbal Orexin-1 Receptors are Involved in Antinociception Induced by Stimulation of the Lateral Hypothalamus in the Formalin Test as an Animal Model of Persistent Inflammatory Pain

Orexin, mainly produced by orexin-expressing neurons in the lateral hypothalamus (LH), plays an important role in pain modulation. Moreover, it is shown that the nucleus accumbens (NAc) is one of the important areas involved in this modulation. Orexin-1 (OX1) and orexin-2 (OX2) receptors are densely...

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Publicado en:Iran J Pharm Res
Main Authors: Jahangirvand, Mahboubeh, Yazdi, Fatemeh, Moradi, Marzieh, Haghparast, Abbas
Formato: Artigo
Idioma:Inglês
Publicado: Shaheed Beheshti University of Medical Sciences 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316264/
https://ncbi.nlm.nih.gov/pubmed/28243282
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