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Progress in HIV-1 Integrase Inhibitors: A Review of their Chemical Structure Diversity
HIV-1 integrase (IN) enzyme, one of the three main enzymes of HIV-1, catalyzed the insertion of the viral DNA into the genome of host cells. Because of the lack of its homologue in human cells and its essential role in HIV-1 replication, IN inhibition represents an attractive therapeutic target for...
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| Publicado no: | Iran J Pharm Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Shaheed Beheshti University of Medical Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316242/ https://ncbi.nlm.nih.gov/pubmed/28243261 |
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