Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G

Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies targeting aquaporin-4 (AQP4-IgG) on astrocytes. We rep...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Yao, Xiaoming, Verkman, Alan S.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316191/
https://ncbi.nlm.nih.gov/pubmed/28212662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0417-9
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