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Using a vector pool containing variable-strength promoters to optimize protein production in Yarrowia lipolytica

BACKGROUND: The yeast Yarrowia lipolytica is an increasingly common biofactory. To enhance protein expression, several promoters have been developed, including the constitutive TEF promoter, the inducible POX2 promotor, and the hybrid hp4d promoter. Recently, new hp4d-inspired promoters have been cr...

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Bibliographische Detailangaben
Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Dulermo, Rémi, Brunel, François, Dulermo, Thierry, Ledesma-Amaro, Rodrigo, Vion, Jérémy, Trassaert, Marion, Thomas, Stéphane, Nicaud, Jean-Marc, Leplat, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316184/
https://ncbi.nlm.nih.gov/pubmed/28212656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0647-3
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