Bmp-12 activates tenogenic pathway in human adipose stem cells and affects their immunomodulatory and secretory properties

BACKGROUND: Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplantation. However, BMPs belong to pleiotropic TGF-β superfamily and have diverse e...

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Publicat a:BMC Cell Biol
Autors principals: Zarychta-Wiśniewska, Weronika, Burdzinska, Anna, Kulesza, Agnieszka, Gala, Kamila, Kaleta, Beata, Zielniok, Katarzyna, Siennicka, Katarzyna, Sabat, Marek, Paczek, Leszek
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316159/
https://ncbi.nlm.nih.gov/pubmed/28214472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-017-0129-9
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