Meta-analysis of quantitative pleiotropic traits for next-generation sequencing with multivariate functional linear models

To analyze next-generation sequencing data, multivariate functional linear models are developed for a meta-analysis of multiple studies to connect genetic variant data to multiple quantitative traits adjusting for covariates. The goal is to take the advantage of both meta-analysis and pleiotropic an...

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Veröffentlicht in:Eur J Hum Genet
Hauptverfasser: Chiu, Chi-yang, Jung, Jeesun, Chen, Wei, Weeks, Daniel E, Ren, Haobo, Boehnke, Michael, Amos, Christopher I, Liu, Aiyi, Mills, James L, Ting Lee, Mei-ling, Xiong, Momiao, Fan, Ruzong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315507/
https://ncbi.nlm.nih.gov/pubmed/28000696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.170
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