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Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

The results obtained in this study establish that liposome formulations incorporating a synthetic polyethylene glycol-derivatized phospholipid have a pronounced effect on liposome tissue distribution and can produce a large increase in the pharmacological efficacy of encapsulated antitumor drugs. Th...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Papahadjopoulos, D, Allen, T M, Gabizon, A, Mayhew, E, Matthay, K, Huang, S K, Lee, K D, Woodle, M C, Lasic, D D, Redemann, C
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1763060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11460
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