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Placental Hypoxia During Early Pregnancy Causes Maternal Hypertension and Placental Insufficiency in the Hypoxic Guinea Pig Model

Chronic placental hypoxia is one of the root causes of placental insufficiencies that result in pre-eclampsia and maternal hypertension. Chronic hypoxia causes disruption of trophoblast (TB) development, invasion into maternal decidua, and remodeling of maternal spiral arteries. The pregnant guinea...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Reprod
Hauptverfasser: Thompson, Loren P., Pence, Laramie, Pinkas, Gerald, Song, Hong, Telugu, Bhanu P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for the Study of Reproduction, Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315426/
https://ncbi.nlm.nih.gov/pubmed/27806942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.116.142273
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