CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes

Diabetic nephropathy (DN) is the major cause of end-stage renal disease worldwide. Podocytes are important for glomerular filtration barrier function and maintenance of size selectivity in protein filtration in the kidney. Podocyte damage is the basis of many glomerular diseases characterized by los...

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Bibliographic Details
Published in:Diabetes
Main Authors: Teng, Beina, Schroder, Patricia, Müller-Deile, Janina, Schenk, Heiko, Staggs, Lynne, Tossidou, Irini, Dikic, Ivan, Haller, Hermann, Schiffer, Mario
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2016
Subjects:
Complications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314701/
https://ncbi.nlm.nih.gov/pubmed/27531950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0081
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