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RNA-seq and metabolomic analyses of Akt1-mediated muscle growth reveals regulation of regenerative pathways and changes in the muscle secretome

BACKGROUND: Skeletal muscle is a major regulator of systemic metabolism as it serves as the major site for glucose disposal and the main reservoir for amino acids. With aging, cachexia, starvation, and myositis, there is a preferential loss of fast glycolytic muscle fibers. We previously reported a...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Wu, Chia-Ling, Satomi, Yoshinori, Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314613/
https://ncbi.nlm.nih.gov/pubmed/28209124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3548-2
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