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Use of broadly neutralizing antibodies for HIV-1 prevention

Antibodies have a long history in antiviral therapy, but until recently they have not been actively pursued for HIV-1 due to modest potency and breadth of early human monoclonal antibodies (MAbs) and perceived insurmountable technical, financial, and logistical hurdles. Recent advances in the identi...

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Dettagli Bibliografici
Pubblicato in:Immunol Rev
Autori principali: Pegu, Amarendra, Hessell, Ann J., Mascola, John R., Haigwood, Nancy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314445/
https://ncbi.nlm.nih.gov/pubmed/28133803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12511
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