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Antisense miR-132 blockade via the AChE-R splice variant mitigates cortical inflammation
MicroRNA (miR)-132 brain-to-body messages suppress inflammation by targeting acetylcholinesterase (AChE), but the target specificity of 3’-AChE splice variants and the signaling pathways involved remain unknown. Using surface plasmon resonance (SPR), we identified preferential miR-132 targeting of s...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314396/ https://ncbi.nlm.nih.gov/pubmed/28209997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42755 |
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