DHHC7 Palmitoylates Glucose Transporter 4 (Glut4) and Regulates Glut4 Membrane Translocation

Insulin-dependent translocation of glucose transporter 4 (Glut4) to the plasma membrane plays a key role in the dynamic regulation of glucose homeostasis. We recently showed that this process is critically dependent on palmitoylation of Glut4 at Cys-223. To gain further insights into the regulation...

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Foilsithe in:J Biol Chem
Main Authors: Du, Keyong, Murakami, Shoko, Sun, Yingmin, Kilpatrick, Casey L., Luscher, Bernhard
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2017
Ábhair:
Membrane Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314192/
https://ncbi.nlm.nih.gov/pubmed/28057756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.747139
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