Potent NLRP3 Inflammasome Activation by the HIV Reverse Transcriptase Inhibitor Abacavir

There is experimental and clinical evidence that some exanthematous allergic drug hypersensitivity reactions are mediated by drug-specific T cells. We hypothesized that the capacity of certain drugs to directly stimulate the innate immune system may contribute to generate drug-specific T cells. Here...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Toksoy, Atiye, Sennefelder, Helga, Adam, Christian, Hofmann, Sonja, Trautmann, Axel, Goebeler, Matthias, Schmidt, Marc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314176/
https://ncbi.nlm.nih.gov/pubmed/28057759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749473
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