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c-JUN Dimerization Protein 2 (JDP2) Is a Transcriptional Repressor of Follicle-stimulating Hormone β (FSHβ) and Is Required for Preventing Premature Reproductive Senescence in Female Mice

Follicle-stimulating hormone (FSH) regulates follicular growth and stimulates estrogen synthesis in the ovaries. FSH is a heterodimer consisting of an α subunit, also present in luteinizing hormone, and a unique β subunit, which is transcriptionally regulated by gonadotropin-releasing hormone 1 (GNR...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Jonak, Carrie R., Lainez, Nancy M., Roybal, Lacey L., Williamson, Alexa D., Coss, Djurdjica
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314163/
https://ncbi.nlm.nih.gov/pubmed/28007961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771808
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