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Accuracy comparison of several common implicit solvent models and their implementations in the context of protein-ligand binding

In this study several commonly used implicit solvent models are compared with respect to their accuracy of estimating solvation energies of small molecules and proteins, as well as desolvation penalty in protein-ligand binding. The test set consists of 19 small proteins, 104 small molecules, and 15...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Mol Graph Model
Main Authors: Katkova, E.V., Onufriev, A. V., Aguilar, B., Sulimov, V.B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313374/
https://ncbi.nlm.nih.gov/pubmed/28064081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2016.12.011
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