ARF confers a context-dependent response to chemotherapy in muscle invasive bladder cancer

Muscle invasive bladder cancer (MIBC) generally responds poorly to treatment and tends to exhibit significant mortality. Here we show that expression of the tumor suppressor p14ARF (ARF) is upregulated in aggressive subtypes of MIBC. Accumulation of ARF in the nucleolus is associated with poor outco...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Owczarek, Tomasz B., Kobayashi, Takashi, Ramirez, Ricardo, Rong, Lijie, Puzio-Kuter, Anna M., Iyer, Gopa, Teo, Min Yuen, Sánchez-Vega, Francisco, Wang, Jingqiang, Schultz, Nikolaus, Zheng, Tian, Solit, David B., Al-Ahmadie, Hikmat A., Abate-Shen, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313321/
https://ncbi.nlm.nih.gov/pubmed/28082400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2621
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