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Lipidomic approach for stratification of acute myeloid leukemia patients

The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing membrane components but these may also alter physicochemical properties of lipid...

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Veröffentlicht in:PLoS One
Hauptverfasser: Stefanko, Adam, Thiede, Christian, Ehninger, Gerhard, Simons, Kai, Grzybek, Michal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313223/
https://ncbi.nlm.nih.gov/pubmed/28207743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168781
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