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Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells

Claudin-2 is highly expressed in lung adenocarcinoma tissues and increases proliferation in adenocarcinoma cells. The chemicals that reduce claudin-2 expression may have anti-cancer effects, but such therapeutic medicines have not been developed. We found that azacitidine (AZA), a DNA methylation in...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hichino, Asami, Okamoto, Miki, Taga, Saeko, Akizuki, Risa, Endo, Satoshi, Matsunaga, Toshiyuki, Ikari, Akira
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313110/
https://ncbi.nlm.nih.gov/pubmed/28057758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762807
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