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The Nucleotide Capture Region of Alpha Hemolysin: Insights into Nanopore Design for DNA Sequencing from Molecular Dynamics Simulations

Nanopore technology for DNA sequencing is constantly being refined and improved. In strand sequencing a single strand of DNA is fed through a nanopore and subsequent fluctuations in the current are measured. A major hurdle is that the DNA is translocated through the pore at a rate that is too fast f...

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Detalhes bibliográficos
Publicado no:Nanomaterials (Basel)
Main Authors: Manara, Richard M. A., Tomasio, Susana, Khalid, Syma
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312860/
https://ncbi.nlm.nih.gov/pubmed/28347003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano5010144
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