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Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans

Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous opioids to exert its analgesic effect using [(11)C]diprenorphine (DPN) positron emission tomography (PET). Patients with...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Sims-Williams, Hugh, Matthews, Julian C., Talbot, Peter S., Love-Jones, Sarah, Brooks, Jonathan CW, Patel, Nikunj K., Pickering, Anthony E.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312788/
https://ncbi.nlm.nih.gov/pubmed/27554530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.08.038
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