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Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation

In skeletal tissue, loss or mutation of the gap junction protein connexin 43 (Cx43, also known as GJA1) in cells of the osteoblast lineage leads to a profound cortical bone phenotype and defective tissue remodeling. There is mounting evidence in bone cells that the C-terminus (CT) of Cx43 is a docki...

詳細記述

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書誌詳細
出版年:J Cell Sci
主要な著者: Moorer, Megan C., Hebert, Carla, Tomlinson, Ryan E., Iyer, Shama R., Chason, Max, Stains, Joseph P.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312734/
https://ncbi.nlm.nih.gov/pubmed/28049723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.197285
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