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Staphylococcus aureus β-Toxin Mutants Are Defective in Biofilm Ligase and Sphingomyelinase Activity, and Causation of Infective Endocarditis/Sepsis

β-toxin is an important virulence factor of Staphylococcus aureus, contributing to colonization and development of disease.(1–3) This cytotoxin has two distinct mechanisms of action: sphingomyelinase activity and DNA biofilm ligase activity. However, the distinct mechanism which is important for its...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biochemistry
Main Authors: Herrera, Alfa, Vu, Bao G., Stach, Christopher S., Merriman, Joseph A., Horswill, Alexander R., Salgado-Pabón, Wilmara, Schlievert, Patrick M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312681/
https://ncbi.nlm.nih.gov/pubmed/27015018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00083
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