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Staphylococcus aureus β-Toxin Mutants Are Defective in Biofilm Ligase and Sphingomyelinase Activity, and Causation of Infective Endocarditis/Sepsis
β-toxin is an important virulence factor of Staphylococcus aureus, contributing to colonization and development of disease.(1–3) This cytotoxin has two distinct mechanisms of action: sphingomyelinase activity and DNA biofilm ligase activity. However, the distinct mechanism which is important for its...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5312681/ https://ncbi.nlm.nih.gov/pubmed/27015018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00083 |
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