Up-regulation of miR-146a increases the sensitivity of non-small cell lung cancer to DDP by downregulating cyclin J

BACKGROUND: Cisplatin (DDP)-based chemotherapy is the common first-line therapy for lung cancer. However, their efficacy is often limited by primary drug resistance and/or acquired drug resistance. The aim of this study was to investigate the function of miRNA-146a (miR-146a) in DDP-resistant non-sm...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Shi, Lin, Xu, Zhaozhong, Wu, Gang, Chen, Xiaoting, Huang, Yuanyuan, Wang, Yanjing, Jiang, Weiqiang, Ke, Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312565/
https://ncbi.nlm.nih.gov/pubmed/28202053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3132-9
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