Soluble Factors Secreted by Endothelial Cells Allow for Productive and Latent HIV-1 Infection in Resting CD4(+) T Cells

In vitro, it is difficult to infect resting CD4(+) T cells with human immunodeficiency virus type 1 (HIV), but infections readily occur in vivo. Endothelial cells (ECs) interact with resting CD4(+) T cells in vivo, and we found previously that EC stimulation leads to productive and latent HIV infect...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Morris, John Henry, Nguyen, Tran, Nwadike, Abuoma, Geels, Mackenzie L., Kamp, Derrick L., Kim, Bo Ram, Boyer, Jean D., Shen, Anding
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312546/
https://ncbi.nlm.nih.gov/pubmed/27599784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2016.0058
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