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The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development

BACKGROUND: Formation of precise neuronal connections requires proper axon guidance. Microtubules (MTs) of the growth cone provide a critical driving force during navigation of the growing ends of axons. Pioneer MTs and their plus-end tracking proteins (+TIPs) are thought to play integrative roles d...

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Vydáno v:Neural Dev
Hlavní autoři: Erdogan, Burcu, Cammarata, Garrett M., Lee, Eric J., Pratt, Benjamin C., Francl, Andrew F., Rutherford, Erin L., Lowery, Laura Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312526/
https://ncbi.nlm.nih.gov/pubmed/28202041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13064-017-0080-7
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