Inactivation of the cholinesterase gene by Alu insertion: possible mechanism for human gene transposition.

The human cholinesterase (ChE) gene from a patient with acholinesterasemia was cloned and analyzed. By using ChE cDNA as a probe, four independent clones were isolated from a genomic library constructed from the patient's DNA. Sequencing analysis of all of the four clones revealed that exon 2 o...

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Bibliographic Details
Main Authors: Muratani, K, Hada, T, Yamamoto, Y, Kaneko, T, Shigeto, Y, Ohue, T, Furuyama, J, Higashino, K
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53125/
https://ncbi.nlm.nih.gov/pubmed/1662391
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