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In vitro generation of Sertoli-like and haploid spermatid-like cells from human umbilical cord perivascular cells

BACKGROUND: First trimester (FTM) and term human umbilical cord-derived perivascular cells (HUCPVCs), which are rich sources of mesenchymal stem cells (MSCs), can give rise to Sertoli cell (SC)-like as well as haploid germ cell (GC)-like cells in vitro using culture conditions that recapitulate the...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Shlush, Ekaterina, Maghen, Leila, Swanson, Sonja, Kenigsberg, Shlomit, Moskovtsev, Sergey, Barretto, Tanya, Gauthier-Fisher, Andrée, Librach, Clifford L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312448/
https://ncbi.nlm.nih.gov/pubmed/28202061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0491-8
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