Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation

Metastasis is the major cause of treatment failure in anaplastic thyroid carcinoma (ATC) patients. In the preliminary study, we demonstrated that interleukin (IL)-11 expression is positively correlated with distant metastasis in ATC. However, the mechanisms underlying remain largely unknown. Here, w...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhong, Zhaoming, Hu, Zedong, Jiang, Yue, Sun, Ruimei, Chen, Xue, Chu, Hongying, Zeng, Musheng, Sun, Chuanzheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312338/
https://ncbi.nlm.nih.gov/pubmed/27487122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10831
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