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The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

Small nucleolar RNAs (snoRNAs) are emerging as a novel class of proto-oncogenes and tumor suppressors; their involvement in tumorigenesis remains unclear. The box C/D snoRNAs U3 and U8 are upregulated in breast cancers. Here we characterize the function of human U3 and U8 in ribosome biogenesis, nuc...

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Publicat a:Oncotarget
Autors principals: Langhendries, Jean-Louis, Nicolas, Emilien, Doumont, Gilles, Goldman, Serge, Lafontaine, Denis L.J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312328/
https://ncbi.nlm.nih.gov/pubmed/27517747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11148
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