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Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer's disease

The apolipoprotein E (APOE) ε4 allele associates with accelerating the conversion from amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD), whereas the protectiveAPOEε2 allele appears to be against the disease. Moreover, entorhinal cortex (ERC) is one of the earliest brain reg...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Jiu, Shu, Hao, Wang, Zan, Liu, Duan, Shi, Yongmei, Xu, Lin, Zhang, Zhijun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312276/
https://ncbi.nlm.nih.gov/pubmed/27542235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11289
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