Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1

The clinical importance of anterior foregut endoderm (AFE) derivatives, such as thyrocytes, has led to intense research efforts for their derivation through directed differentiation of pluripotent stem cells (PSCs). Here, we identify transient overexpression of the transcription factor (TF) NKX2-1 a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Dame, Keri, Cincotta, Steven, Lang, Alex H., Sanghrajka, Reeti M., Zhang, Liye, Choi, Jinyoung, Kwok, Letty, Wilson, Talitha, Kańduła, Maciej M., Monti, Stefano, Hollenberg, Anthony N., Mehta, Pankaj, Kotton, Darrell N., Ikonomou, Laertis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312259/
https://ncbi.nlm.nih.gov/pubmed/28162994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.12.024
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados