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Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury

We previously showed the efficacy of multiple research cell lines (RCLs) of human CNS neural stem cells (HuCNS-SCs) in mouse and rat models of thoracic spinal cord injury (SCI), supporting a thoracic SCI clinical trial. Experts recommend in vivo preclinical testing of the intended clinical cell lot/...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Reports
Autori principali: Anderson, Aileen J., Piltti, Katja M., Hooshmand, Mitra J., Nishi, Rebecca A., Cummings, Brian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312249/
https://ncbi.nlm.nih.gov/pubmed/28199829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.12.018
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